Here are 9 of the worst medical afflictions!
#9 Calcified Bladder What's worse than a parasitic worm infection?
A parasitic worm infection that causes a "calcified bladder" — a condition that probably feels
every bit as uncomfortable as it sounds.
Just remember, when we say a "calcified bladder" we really mean a bladder, that
has turned, or is slowly turning to stone.
A 43-year-old man in Qatar found out just how excruciatingly uncomfortable a calcified
bladder can be.
He had blood in his urine and pain when he peed for a month before doctors diagnosed
him with an infection by the parasite Schistosoma, which is transmitted by freshwater snails.
Eggs of the parasite ended up on the wall of the man's bladder, and his body's immune
response caused these areas of the bladder wall to become calcified in a pattern known
as "eggshell calcification,".
This is one of those weird instances when the human body gets it very wrong.
It's trying to combat something, but ends up turning one of your most important most
delicate organs into a giant rock!
While this kind of calcification as a result of schistosomiasis isn't rare, it is unusual
for doctors to see a patient with an entire bladder encased in calcium, since it takes
years for that much calcium to build up inside the body.
The patient's doctors suspected that the man actually became infected with the parasite
as a child and that he lived with it for at least 30 years before doctors prescribed a
treatment.
Go to the doctor guys if you ever feel a funny pain!!
#8 elephantisasis This is a rare, but surprisingly well known
affliction.
Okay, technically elephantisasis is only a very unfortunate symptom of something else.
Let me explain: The root cause of this condition is worms.
A parasitic worm known as a filarial worm that's transmitted into the bloodstream
via a mosquito bite.
Most people will live with this parasite without ever really noticing any symptoms.
Others aren't so lucky…
Some people develop a syndrome called elephantiasis, which is marked by severe swelling in the
arms, legs, or genitals.
And when I say swelling, I mean serious swelling!
It's not called elephantiasis for nothing.
The skin may also become thicker, and the condition is extremely painful.
There are medications available to kill the parasite, so early intervention will of course,
produce the best result.
There apparently are surgical options if the elephantiasis affects the testicles, but not
the limbs.
I guess THAT'S comforting…..pfffft!
#7 Disappearing Face If you seem to be spontaneously transforming
into a Superman villain without having a chemical accident to blame for your new, scary, imploding
face— you may just have Parry-Romberg syndrome.
This terrible condition makes the skin and soft tissues of half of your face slowly cave
in.
The worst part is, just because sometimes nature likes to be extra nice, generally only
half of your face caves in.
You end up looking like half your face got stampeded by elephants (or people with elephantiasis
for that matter).
Since caving half your face in isn't obviously enough, Parry-Romberg syndrome also discolors
the skin, sinks your eyeball back into your skull, and causes your jaw to stop opening
properly.
And, just in case that isn't enough torture, some people experience additional side effects
such as migraines, seizures, and muscle spasms in the "regular" half of their face.
Parry Romberg Syndrome is a type of Lipodystrophy.
Lipodystrophy translates to "fat loss," which you'd normally think of as a good thing -- right
up until you lose all of it.
See, a nice layer of fat is what gives your face everything that makes it recognizable
-- such as cheeks and lips.
Lipodystrophy is a common side effect of powerful antiretroviral drugs, meaning that if you
happen to be fighting HIV, the universe still isn't quite finished kicking you in the balls.
You could end up with a concaving face along with your collapsing immune system.
Don't think you're safe from this condition by avoiding HIV however: There are dozens
of factors, ranging from environmental to genetic, that could cause you to transform
into Skeletor without warning.
#6 Water Allergy
As the majority of our body is made out of water, it seems impossible that an allergy
to water could even exist.
But impossible means nothing on this list.
You may argue that Aquagenic ur-tih-care-ee-al isn't a true pure blood allergy because
it doesn't trigger a histamine response.
Okay, fine, but there is the development of itchy hives and welts even after mere minutes
of water exposure.
This condition is very rare, and the cause still hasn't been properly established.
Scientists have speculated that the water itself isn't the cause, but rather specific
chemicals or impurities that are ubiquitous within the water are the root cause.
However, even purified water can trigger a reaction for certain individuals.
Sooooo, that brings us back to blaming water.
The most common treatment is topical application of capsaicin, which is used to relieve pain.
Ultraviolet radiation is also commonly used alongside antihistamines to help rid the patient
of lesions and outbreaks caused by this condition.
This therapy will cause thickening of the epidermis which can prevent water from penetrating
this layer and interacting with the cells underneath.
#5 Clarkson's Disease Can you imagine…….people blow up and expand
like human water balloons.
If there was ever something you don't want to hear from your doctor it would be the phrase
"you are leaking".
If it's something you don't want your car or your fridge doing, it's a pretty safe bet
that you don't want your body to be doing it either.
If you do happen to hear that from your doctor, unfortunately, you may be dealing with Clarkson's
disease.
Clarkson's disease is also known as systemic capillary leak syndrome.
As the name suggests, it's what happens when your blood vessels start leaking plasma all
of a sudden.
Yes, and the "plasma" doesn't refer to blood either.
All that extra fluid has nowhere to go but into the sponge-like tissues of your skin
and vital organs.
So you just start expanding.
Episodes typically take around three days to reach a peak, a time where you'll go from
your normal usual self to a bloated, squishy walrus-like version.
The only treatment is to basically just wait.
And just in case that's not terrifying enough, you should know that it doesn't take much
to go from just plain bloated to dead and bloated: Every single episode has the potential
to straight-up pop one of your vital organs!
Scientists actually know very little about what causes this condition.
There's no real pattern as to whom and when it strikes, although we do know that it usually
develops after an upper-respiratory infection -- so the next cold you catch may be the one
that turns you into a swollen sack of blood and nightmares.
The only thing we know for certain is that once you have your first attack, it won't
be your last.
You will most likely have to spend the rest of your life randomly inflating and deflating.
#4 Fibrodysplasia ossificans progressiva
Fibrodysplasia ossificans progressiva is a progressive genetic disorder that turns soft
tissues into bone over time.
Remember that guy whose bladder turned into a giant stone?
Well this is pretty much the same…but all over the body!
The gene found in bone, muscles, tendons, and ligaments regulates growth and development
of those tissues, and is normally responsible for turning cartilage into bone as children
develop.
However, mutations of this gene can allow ossification to go unchecked, which can even
turn skeletal muscle into bone and cause joints to fuse together.
The disease is caused by a mutation of the body's repair mechanism, which causes fibrous
tissue, which includes muscle, tendon, and ligament, to be ossified spontaneously or
when damaged.
In many cases, injuries can cause joints to become permanently frozen in place.
So if you break an arm or something worse...it just freezes itself together in the awkward
broken position.
Surgical removal of the extra bone growths has also been shown to cause the body to "repair"
the affected area with even more bone.
Unfortunately, that awkward broken area tends to get chunkier with time.
This disorder occurs in about 1 in 2 million people, and there are currently no treatments
or cures.
Trauma exacerbates the condition, and again, any attempts to remove bone surgically just
results in the body producing even more bone in the area.
Basically, anyone with this condition is definitely not participating in any contact sports.
#3 Epidermodysplasia verruciformis
What appears to be tree bark growing out of someone's skin is actually a condition called
Epidermodysplasia verruciformis.
Of course, it isn't actually tree bark, but it's just stuff that sure looks a lot
like it unfortunately!
These tree-like growths are actually just very extreme warts that can be exacerbated
by exposure to sunlight.
While these warts may be benign early in life, they can become malignant later in life.
The warts are caused by a rare mutation of the EVER1/EVER2 genes.
Though the function of the genes isn't really well-understood, the mutations cause the skin
to be extremely susceptible to human papilloma viruses 5 and 8, which typically don't cause
disease.
While there are some treatment options available to mitigate the symptoms, there is no cure.
Oh…and yes that was HPV…as in the STD that 80% of sexually active people have!
#2 Cutaneous Horn
Can you imagine a person with horns growing out of their head?!
The people that you happen to see with this incredibly rare affliction will be walking
around with little horns on their eyelids, or even with a single big horn on their foreheads.
These people are suffering from keratinous skin tumors with the appearance of horns,
or sometimes of wood or coral.
The cause of cutaneous horns is still unknown, but it's believed that exposure to radiation
can trigger the condition.
This is evidenced by a higher rate of cases occurring on the face and hands - areas that
are often exposed to sunlight.
Other cases have reported cutaneous horns arising from burn scars.
Some researchers actually believe that it's caused by a particular strain of HPV.
You know, that pesky STD that most people have that we discussed before.
So, yeah.
Technically your figurative horniness, which could lead to recklessness, which in turn
could lead to literal horniness!!
#1 Xeroderma pigmentosum
This condition, in a nutshell, is a hypersensitivity to sunlight.
Almost all exposure to ultraviolet light, which is something inevitable living on planet
earth, leads to severe skin damage and the formation of various skin cancers.
This in effect is living the life of a vampire, except without the benefits of being an actual
vampire.
Xeroderma pigmentosum, or XP, is a rare autosomal recessive genetic disorder of DNA repair in
which the ability to repair damage caused by UV light is deficient.
In extreme cases, all exposure to sunlight must be forbidden, no matter how small; as
such, individuals with the disease are often colloquially referred to as "Moon children".
This disease is present in both genders and in all races, with an incidence of about 4
cases for every million people in the United States.
XP is roughly six times more common in Japanese people than in other groups.
The most obvious, and often important part of treatment, is avoiding exposure to sunlight.
This includes wearing protective clothing and using sunscreen, physical and chemical.
Unfortunately, fewer than 40% of individuals with the disease survive beyond the age of
20.
Some XP victims with less severe cases do manage to live well into their 40s however.
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