From the same study; "Thymoquinone extracted from black seed triggers apoptotic cell death
in human colorectal cancer cells via a p53-dependent mechanism."
Still from the same study, "These results indicate that TQ is antineoplastic and pro-apoptotic
against colon cancer cell line HCT116.
The apoptotic effects of TQ are modulated by Bcl-2 protein and are linked to and dependent
on p53.
Our data support the potential for using the agent TQ for the treatment of colon cancer."
Meaning the black seed oil is killing cancer cells!
REF – 'Thymoquinone extracted from black seed triggers apoptotic cell death in human
colorectal cancer cells via a p53-dependent mechanism'
From a 2003 study we find, "Thymoquinone inhibits autophagy and induces cathepsin-mediated,
caspase-independent cell death in glioblastoma cells."
More cancer cell killing evidence.
From another study in 2003 the good news for epilepsy sufferers is, "These findings demonstrate
that the volatile oil of N. sativa has the ability to inhibit colon carcinogenesis of
rats in the postinitiation stage, with no evident adverse side effects, and that the
inhibition may be associated, in part, with suppression of cell proliferation in the colonic
mucosa"
The very best research on the effect of black cumin on cancers was conducted via a review
of research papers in 2011.
In this study the role of black cumin as an anti-cancer agent is explained thus, "Many
active ingredients have been found in the seeds of N. sativa.
The seeds contain both fixed and essential oils, proteins, alkaloids and saponin described
the quantification of four pharmacologically important components: thymoquinone (TQ), dithymoquinone
(DTQ), thymohydroquinone (THQ), and thymol (THY), in the oil of N. sativa seed by HPLC.
Much of the biological activities of the seeds have been shown to be due to thymoquinone,
the major component of the essential oil, which is also present in the fixed oil"
In a review study the researchers have offered up 57 reviewed research papers on this subject
and found black cumin to be effective against these cancers;
– Blood cancer – El-Mahdy et al. (2005), Effenberger et al. (2010), Swamy and Huat
(2003) – Breast cancer – Farah and Begum (2003),
(El-Aziz et al., 2005), Effenberger et al. (2010)
– Colon
cancer – Gali-Muhtasib et al. (2004), Salim and Fukushima (2003), Norwood et al. (2006)
– Pancreatic cancer – Chehl et al. (2009), Banerjee et al., (2009), Torres et al. (2010)
– Hepatic cancer – Thabrew et al. (2005), Nagi and Almakki (2009)
– Lung cancer – Swamy and Huat (2003), Mabrouk et al. (2002)
– Leukemia – El-Mahdy et al. (2005) – Skin cancer – Salomi et al. (1991)
– Fibrosarcoma – Badary and Gamal (2001) – Renal cancer –
Khan and Sultana (2005) – Prostate cancer – Kaseb et al. (2007),
Yi et al. (2008) – Cervical cancer – Shafi et al. (2009),
Effenberger et al. (2010)
Already Getting Chemotherapy?
You might want to have a look at the study from
2010 that tested the effectiveness of protection afforded by black cumin against the toxicity
of the drug cyclophosphamide.
The researchers stated, "These results suggest that administration of NSO or TQ can lower
CTX-induced toxicity as shown by an up-regulation of antioxidant mechanisms, indicating a potential
clinical application for these agents to minimise the toxic effects of treatment with anticancer
drugs"
Protection Against Radiotherapy In 2009 in
a study of 60 rats, it
was found that, "Our results strongly recommend
Nigella sativa oil as
a promising natural radioprotective agent against immunosuppressive and oxidative effects
of ionizing radiation."
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