Hi - this is Kate from MinuteEarth.
In the United States alone, 22 people die every day waiting for a kidney, liver, heart,
or lung transplant.
There simply aren't enough donated human organs to go around, and we can't just go
around stealing them out of random healthy people.
But pigs' organs have roughly the same structure and proportions as human organs – and we
already kill half a billion of the creatures every year for food – so why can't we
just use their organs?
Here's the thing - our immune systems are really, really good at seeking out and destroying
anything foreign to our bodies, so even human-to-human organ transplants sometimes get rejected.
And pig organs are much foreign-er: they have a super-conspicuous sugar molecule on the
surface of their cells that's basically a "fight me" sign for humans' organ-rejecting
antibodies.
But we've actually been able to engineer pigs whose organs don't carry those sugars, so
assuming we could take care of pig organs' other "fight me" signs in similar ways,
we might one day be able to transplant pig organs into humans.
But there's a far more radical idea for pork-based organ farming: grow customized human organs
in pigs.
Actually, it's not just an idea – it's an ongoing experiment in real life.
First, we engineer a pig embryo that doesn't grow its own kidneys.
Then, we inject it with stem cells from the person needing a transplant.
Then, as the modified pig embryo develops, those human cells grow inside the oinkubator
into healthy kidneys made from the patient's own cells.
At least, that's the plan.
So far, we've only seen this experiment all the way through when the modified pig
embryos were injected with stem cells from other pigs.
We don't know whether it'll actually work with human kidneys, because we've halted
all experiments with the pig-human embryos after just four weeks of development, because...some
of those human stem cells could develop into other human organs elsewhere in the pig's
body - which raises a lot of ethical questions, like what to do with them.
Even if the cells don't migrate and these hybrid pigs end up producing lots of live-saving
organs, what rights do we give to a part-human pig, even if the part is just a kidney?
What if it's two kidneys?
Two kidneys, a liver, and a set of lungs?
In principle, we could use the same technology to grow human hearts, human spinal cords,
and even human brains - all inside of a pig.
And when we do, how will we know if that pig is still a pig?
This episode of MinuteEarth is supported in part by Tab for a Cause.
If you're like me, you open a lot of tabs in your browser.
Tab for a Cause is a browser extension that donates to charity with each new tab you open,
which means lots of money for nonprofits like Conservation International and Human Rights
Watch - without costing you a thing.
The last time we featured Tab for a Cause, MinuteEarthings like you raised more than
$10,000 - click the link in the description to help us do even better this time.
And while you're down there, will you find the notification bell next to the subscribe
button, and click on it?
YouTube has changed the way it notifies subscribers, and this is the best way to make sure you
find out when we post a new video.
You can do the same thing on your phone or tablet.
If you don't see the bell, make sure you're subscribed in the first place.
Thanks, and see you next time!
For more infomation >> Should We Grow Human Organs In Pigs? - Duration: 3:19.-------------------------------------------
YOU NEED THIS! 2017 Nissan Sentra NISMO REVIEW - Duration: 4:08.
every generation of the nissan sentra
sent the early 1990s proudest 40 variant
most of the potted up small cars have
worn the FDR batch rename that earned a
fair share of credibility after the b13
generation sentra se-r captured
enthusiasts parts and appeared more than
once on TV and best cars list thanks to
hike on your dollar ratio now and it's
pumping up is no performance on nissan's
put the name on the latest offensive
performance very it helps make a
connection among all of the sun's
performance-oriented offering was
probably the juke nismo and Loretta the
370z Nismo and the top dog
600-horsepower gt-r Nismo but the center
and his MO is not a racetrack slaying
high-performance be far from it in fact
given that it has just 188 horsepower
and 177 pounds to put of torque from the
one got six litre turbocharged
four-cylinder that's the lesson was
offered in the last century fer
available from 2072 2012 which had 200
horsepower and 180 pounds to foot of
torque from a to God five liter
four-cylinder engine it's also far short
of the books wagon GI 210 or 220
horsepower the Ford Focus that's key 252
horsepower and the subaru WRX 268
horsepower
of course power isn't everything
particularly considering the center and
is most estimated starting price of less
than twenty-five thousand dollars after
all cars like the 197 horsepower ford
fiesta st prove that outright speed is
far from his sole measure of a card fun
factor to that end is more went to work
on the center's chassis compared with
the identically powered sentra sr
turboed the mismo has a slightly lower
ride height difference springs in
Richmond dancers additional structural
bracing and one inch larger wheels shot
with 215 / 45 r18 ultra high performance
all-season tires summer tires are
available as a dealer and tall adoption
after a quick drive around Los Angeles
in the center is mom we're pretty
Vincent it won't unsee our current
favorites such as the GI but that's not
to say there's nothing to like about the
nismo the little one Coptic liter
engines ft enough once on the boil
there's some turtle like download the
range but the six-speed manual has
relatively short hearing that makes it
easy to keep the engine in the need of
historic curve
there's also a continuously variable
automatic transmission available as a no
cost options we didn't get the chance to
drive a centrist ill-equipped but we can
safely say we pack on that transmission
we do wish mismo had gone a bit further
with the shaft retweet turning could be
sharper and steering feel is nothing to
write home about the nismo suspension is
noticeably different live lesser
centrist but it's tuning seems to
negatively impact ride quality more than
improve handling prowess the likeness of
control the series shifters and clutch
combined to make the center-field
possible leave netted eight-page push
harder and its economy car routes become
all too obvious
-------------------------------------------
Education Panel Advances Tax Credits for Private School Tuition - Duration: 2:08:28.
For more infomation >> Education Panel Advances Tax Credits for Private School Tuition - Duration: 2:08:28. -------------------------------------------
Browse coloring antistress from Aliexpress - Duration: 2:42.
Anti-stress coloring is the direction, which very quickly gained its popularity.
A fairly simple but effective method to remove anxiety
and creativity for adults and children.
Today I show the review of the coloring antistress "Alice in Wonderland".
Goods AliExpress
Reviews
Hello!
You at the channel "Goods AliExpress".
On Aliexpress you can find a very large variety of coloring books at affordable prices.
The number of minimal pages that I had found, was 24, with the cost from $1.34.
Coloring book on 80 pages, called "Alice" I bought for $11.39.
Cover and leaves of the notebook are pretty tight,
so crayons and markers are not interrupted on the other side.
The drawings are very interesting and varied.
Contain, as little details that need more attention, and large.
Of course, they are all on the theme of fairy tale "Alice in Wonderland".
Anti-stress coloring pages for adults are a great way of relaxing,
meditation, and entry into the stress space.
This coloring is more complex than normal children,
so it will be interesting for people of any age.
I was left in awe.
The pictures are very beautiful and bright.
It all depends on your imagination.
To buy anti-stress coloring, you can by link in the description.
And don't forget to subscribe and like this review =)
-------------------------------------------
La bella e la bestia - la bracca furiosamente - Duration: 1:03.
For more infomation >> La bella e la bestia - la bracca furiosamente - Duration: 1:03. -------------------------------------------
Peugeot 108 ACTIVE 1.0 E-VTI 68PK 5-DRS * AIRCO * - Duration: 0:43.
For more infomation >> Peugeot 108 ACTIVE 1.0 E-VTI 68PK 5-DRS * AIRCO * - Duration: 0:43. -------------------------------------------
Citroën C4 Cactus E-VTI 82 BUSINESS ETG/AUTOMAAT - Duration: 1:37.
For more infomation >> Citroën C4 Cactus E-VTI 82 BUSINESS ETG/AUTOMAAT - Duration: 1:37. -------------------------------------------
Mercedes-Benz E-Klasse 300 BLUETEC HYBRID AMG EDITION , Full options [NET - Duration: 1:49.
For more infomation >> Mercedes-Benz E-Klasse 300 BLUETEC HYBRID AMG EDITION , Full options [NET - Duration: 1:49. -------------------------------------------
Software #BIM desenho arquitetônico 3D - #Edificius #007 - Duration: 0:58.
For more infomation >> Software #BIM desenho arquitetônico 3D - #Edificius #007 - Duration: 0:58. -------------------------------------------
IERI VS OGGI - FRANCESCO PAPPA - Duration: 3:15.
For more infomation >> IERI VS OGGI - FRANCESCO PAPPA - Duration: 3:15. -------------------------------------------
Buongiorno in Salute - Rai 3 - 25 gennaio 2017 - Istituto Auxologico - Duration: 3:51.
For more infomation >> Buongiorno in Salute - Rai 3 - 25 gennaio 2017 - Istituto Auxologico - Duration: 3:51. -------------------------------------------
Vitamin E | Masterclass With Masterjohn 1.4 - Duration: 23:18.
Hi. I'm Dr. Chris Masterjohn of
ChrisMasterjohnPhD.Com and you're
watching Masterclass With Masterjohn.
This is the fourth in a series of videos
on the antioxidant defense system and
today we are for the first time looking
at a specific component of that system in
detail and we're starting with vitamin E.
You can see the structure of vitamin E
on the screen and what's shown is alpha-tocopherol.
Vitamin E actually comes
in eight forms and it can be split between
tocopherols and tocotrienols. Within
each of those we have four subforms:
alpha, beta, gamma, and delta. If you see
that there's a ring structure on the
left and a tail structure on the right
the tail structure of all the tocopherols
is the same and it differs from the
tail structure of tocotrienols in
that tocopherols have a saturated tail
and tocotrienols have double bonds in
this tail that makes it unsaturated. The
difference between alpha, beta, gamma, and delta
is in the ring structure.
Alpha-tocopherol has three methyl groups in the
ring structure. All of the other tocopherols
have fewer than that, and they
differ based on the number and position
of those methyl groups. If you were to
compare alpha-tocopherol to gamma-tocopherol
that difference in
methyl groups would be what you
see different between them. But if you
compare alpha-tocopherol to
alpha-tocotrienol, the ring structure will be
exactly the same and it will be the tail
structure that differs. The name "tocopherol"
comes from the Greek "tokos"
meeting "birthgiving ," "fero" "to carry,"
and the suffix "-ol," which means it's an
alcohol. In chemistry, anything that has a
hydroxyl group, OH, is an alcohol and
so the name tocopherol means an
alcohol that helps a mother carry a
pregnancy to term and give birth. And
that's because when we first discovered
vitamin E deficiency it was associated with
infertility. now tocotrienol is a
later name where "triene" means three
double bonds and that refers to the
number of double bonds that are in the
tail and that's where that name comes from.
Although vitamin E was originally
known as the fertility vitamin, we now
know from its chemistry that its
function is to convert lipid peroxyl
radicals to lipid peroxides and thereby
avert lipid peroxidation chain
reactions in cellular membranes.
This is the only well-established role
as a direct antioxidant in this context.
There are a lot of other things that we
believe vitamin E does, like
regulate gene expression, but it's not
clear if it does them independently from
this process because oxidation and lipid
peroxidation affects many other cellular
processes. So to date there's no real
clear evidence that vitamin E does
anything that can't be traced directly
to its role as an antioxidant in this
context. And so we can look at the
infertility that originally came with
vitamin E deficiency and we can say that
was due to lipid peroxidation. Similarly, we
could say lipid peroxidation is believed
to play a role in many other chronic
degenerative diseases that are more
common today and so wherever you see
oxidative stress and lipid peroxidation
there's good reason to think vitamin E
may be protective. Because vitamin E's
role is to protect PUFAs, then you
can see in the food supply foods that have
more PUFA in them will tend to have
more vitamin E. But it doesn't all come
in the same ratio, and the ratio of
vitamin E to PUFA in the diet may be more
important than the amount of vitamin E
itself. If you look at the RDA for vitamin E,
for most adults, it's 15 milligrams per
day, but that can vary with lactation and
pregnancy and it can vary with age. We
see that the RDA takes into contextual
factors sex, age, pregnancy, and lactation
but not PUFA intake. That can be misleading
because if you look at the actual DRI
report you can see that they clearly
believed
that vitamin E requirements depend
on PUFA intake. This is a direct quote from
the report that underlies the current
RDA for vitamin E. "Vitamin E requirements
"have been reported to increase when
"intakes of polyunsaturated fatty acids (PUFAs)
"are increased. Based on these data it
"was suggested that a ratio of at least
"0.4 milligrams alpha-tocopherol
"per gram of PUFA should be consumed. However, the
"method of determining the vitamin E
"requirement generated by PUFA intake is
"not universally accepted because the
"amount of vitamin E required to
"stabilize PUFAs in tissues is
"influenced to a greater extent by their
"degree of unsaturation than by their mass."
What that means is that you can consume
linoleic acid from vegetable oil that has
two double bonds, but you can also
consume EPA from fish oil that has
five double bonds or DHA from fish oil
that has six double bonds. EPA and DHA are
more vulnerable to peroxidation than
linoleic acid because they have more
double bonds.
"Moreover PUFAs are not deposited in
"the tissues in the same proportions that
"they occur in the diet." In other words
you eat a given amount of PUFA but
it's not the amount you eat, it's the
amount that winds up in membranes that
actually makes you need more vitamin E.
One is influenced by the other but it's not
the same as the other. They go on, "Finally,
"dietary PUFAs are modified by elongation
and desaturation . . . " That means you can eat
linoleic acid but then you can make
it longer and introduce more double
bonds and turn it into something like
arachidonic acid, which is more
vulnerable to peroxidation, or you can
consume something like alpha-linolenic acid
and convert it, from flax oil, and
convert it to EPA or DHA, which is longer
and has more double bonds and it's more
vulnerable to peroxidation. They go on, ". . . and
"are catabolized to various degrees
depending on energy status." That means if
you're in a caloric deficit you're going
to burn PUFAs for energy and so they're
not going to influence your
vitamin E requirement but if you're in a
caloric excess you're going to store them
in your membranes more often or in your
adipose tissue and that is going to
influence your vitamin E requirement.
They conclude, "Although it is clear that
"the relationship between dietary vitamin E
"need is not simple, high PUFA intakes
"should certainly be accompanied by
increased vitamin E intakes." How often
do you see scientists say "certainly"? Not very
often. So this is really important
because if you just look at the RDA
itself PUFA is nowhere to be seen, but if
you read the report they state clearly
that the reason they didn't express the
RDA per gram PUFA is because there's no
straightforward mathematical calculation
to express it in that way, but the
principle that the more PUFA you eat
the more vitamin E you need is solid, so
solid they call it "certain." Now that's
really important because if you look at
how vitamin E is distributed in foods
you get a very different picture if you
express it per gram PUFA than if you
express it
total amount in the food. The data that's
on the screen, I used alpha and
gamma tocopherol because these are the
major forms of vitamin E that are
important, but you'd get similar results if
you just looked at alpha tocopherol or
if you took total vitamin E.
What you see is that when you only look
at the amount of vitamin E in the food
wheat germ oil looks way better than
everything else. Corn oil is pretty hot
itself, palm oil is pretty good, but not
as good as corn oil, butter's terrible, olive
oil's kind of "eh." But if you express that per gram PUFA
what you see is that all the sudden
palm oil is the best, butter is still not as
good as olive oil but the difference is
isn't as big, and wheat germ oil no longer takes
the lead.
Well, when we're looking at something
like butter
we also have to take into account what
was the cow eating? And when cows eat grass,
which is high in photosynthetic activity,
they wind up with more vitamin E in their
meat and their butter when when they eat grain.
So let's take a look at what's happening
in photosynthesis to
see why that's the case. In
photosynthesis, we take energy from
sunlight and we combine hydrogen from
water with carbon and oxygen from carbon
dioxide and that makes sugar. There's
some oxygen left over and that gets
released into the atmosphere but oxygen
in high concentrations, especially in the
presence of ultraviolet light from the
sunlight, can be converted into reactive
oxygen species like superoxide and
hydrogen peroxide. The plant requires
vitamin E to protect its PUFAs from the
reactive oxygen species just like we do.
So a plant that has high photosynthetic
activity needs a lot of vitamin E to
protect against that oxidative liability
from oxygen and the ultraviolet light. So
if we add corn as representative of
grains and lettuce as representative of
greens to our chart, we see that they're
meaningless if you look at total vitamin E.
But if you look at vitamin E per
gram PUFA, lettuce as a leafy green
comes out way ahead of most other things
on this list, even ahead of palm oil. Now for
humans,
we're not going to eat lettuce as most of
our calories so that's not that
important for directly eating it, but when we
think about the animal products we use, a
cow can eat most of its calories as grass
and so if the cow is eating grass instead
of eating grain, the cow's going to get a
lot more vitamin E in its diet, and
that's because this grass is heavily
photosynthesizing so its PUFAs are very
vulnerable,
whereas the grain not only is it not
photosynthesizing but it's metabolically
dormant so there's very little risk of
PUFAs getting harmed by reactive
oxygen species. If you look across
studies at the vitamin E contents of
grass-fed and grain-fed beef, you see
grass-fed always comes out on top.
Whether it's four versus less than 1, 3
versus 1.5, 2 versus less than 1, and so on
grass-fed beef is generally 1.3-5.4-fold
higher in vitamin E than grain-fed beef.
Similar results you'd get from butter, and that
reflects the fact that cows that eat grass are
eating photosynthetic tissues that need a
lot of vitamin E and therefore contain
a lot of vitamin E and provide a lot
of vitamin E to the cow. If we add into our
list of fats and oils grass-fed butter
then it comes out a little bit better
than olive oil, way better than butter
from cows fed hay, or average
butter that you find in the supermarket
and although it's not as good as palm
oil it's better than corn oil. and it's
pretty competitive with wheat germ oil.
So the vitamin E to PUFA ratio matters a lot
and the method of production matters.
If we look at how vitamin E is digested
absorbed and transported, it has some
implications for our diet.
Let's take absorption first. If this
cylinder is the small intestine, we eat
vitamin E and it's incorporated with bile
acids and pancreatic enzymes into what
we call the mixed micelle. That then is
absorbed into the intestinal cell and
repackaged. Now what is stimulating the
production of the mixed micelle and the
bile acids and the pancreatic enzymes is
primarily the fat in our diet. If you
think about the amount of fat we eat in a meal,
it's measured in grams. You think about
the amount of vitamin E we eat in a meal,
it's measured in milligrams. So there's way more stimulus
from the fat to stimulate the
fat-digestion machinery than there is from the
vitamin E, and so that fat says to our
bodies, "make more bile acids, make more
"pancreatic fat-digesting enzymes, create
"more machinery to make the mixed micelle."
That helps us absorb vitamin E. What you see
on the screen is data from a study where
subjects were given either a fat-free
meal, a low-fat meal, or a full-fat meal.
and they tested how much vitamin E did
they absorb. The fat-free meal was just an
apple with a vitamin E supplement, the low-fat
meal was the same thing plus
a bagel with low-fat cream cheese
and the full-fat meal was the same thing
only the cream cheese was full-fat instead
of low-fat. The high-fat meal wasn't
really that high in fat, it was 21% of
calories,
but it was a lot higher than the low-fat
meal, which was six percent of calories.
On the left you can see that they absorbed
10% of vitamin E when it was in a fat-free
meal, twenty percent with the low-fat
meal, and 33 percent with the high-fat
meal, so by bringing fat from 0 to 6 to 21
percent of calories you get this
graded increase and you triple your
absorption of vitamin E by including the
full-fat cream cheese. Now maybe if they
had eaten thirty or forty percent of
their calories they would have absorbed
even more but the principle here is the
more fat you eat the greater proportion of
vitamin E you're going to absorb from the
diet. If you're just eating natural foods I
would say that means eat some fat, you
don't have to eat a really high-fat diet but
you should have some fat in your diet
to make sure you're absorbing your
vitamin E. If you're going to take a vitamin
E supplement, you should take it with
the largest meal of the day, and if your
fat varies a lot between different meals
you should take it with the meal that has the
greatest amount of total fat to maximize
its absorption. Now if we come back to
this slide we see that after vitamin E
is absorbed it gets repackaged in
intestinal cells into chylomicrons. Those
go into the lymph and then into the
blood and when they go into the blood
they can be taken up by peripheral
tissues, meaning tissues other than the
liver in this case, where the vitamin E
can be exchanged with other lipoproteins
like LDL and HDL, but most of it is
going to get taken up by the liver. Now
the liver has a protein called alpha-tocopherol transfer protein
or alpha-TTP that
recirculates the vitamin E into VLDL
particles that go back into the blood.
That VLDL can deliver alpha-tocopherol
or other forms of vitamin E to the
peripheral tissues again and eventually
it's digested into LDL. And this first uptake
by peripheral tissues from the chylomicrons
is relatively minor compared to the
amount of vitamin E that's taken up
by VLDL and LDL in the time after the
vitamin E has gone through the liver and
recirculated with alpha-TTP. Now this is
important because there's a rare genetic
defect in alpha-TTP that makes it really
hard to get enough vitamin E from a natural
diet pretty much impossible so you have to
supplement really high doses of vitamin E to
overcome it and it also makes it really
hard to get that vitamin E into the brain
because alpha-TTP also plays a role in
getting vitamin E into the brain.
But for people who don't have any
genetic defects alpha-TTP also makes it, has
some important implications for how we
think about what we want to eat.
for vitamin E. The data on the screen
shows the affinity of alpha-TTP for the
different forms of vitamin E. Alpha-tocopherol
is arbitrarily set at a hundred
percent and everything else is expressed
as a percent affinity compared to alpha-tocopherol.
As you go from alpha to beta to
gamma tocopherol, you go from a hundred to
38% to 9%. So alpha-tocopherol
has ten
times more affinity for alpha-TTP than gamma-tocopherol.
If you go from tocopherol to
tocotrienol, again alpha-tocopherol
has ten times more affinity than alpha-tocotrienol
so alpha-tocopherol
is overwhelming recirculated in
preference to all the other forms. If we
look at standard diets,
most people are consuming more gamma
tocopherol than alpha-tocopherol, but once
it goes to their liver alpha-TTP
recirculates a lot more alpha-tocopherol
than gamma-tocopherol, and so in the blood
of people eating a standard diet
there's a lot more alpha-tocopherol
than gamma-tocopherol. The alternative to
recirculation by alpha-TTP is enzymatic
degradation to metabolites that are
excreted in the urine. So if you look at
people on a standard diet they have far more
gamma-tocopherol metabolites in their urine
than they do alpha-tocopherol
metabolites.
Well why does it seem that our bodies
are trying to concentrate alpha-tocopherol?
What you see on the screen is a comparison
of the structures of alpha and gamma.
Alpha is on the top and gamma's on the bottom.
Alpha-tocopherol has three methyl groups
whereas gamma tocopherol only has two and in
place of the third it just says a
hydrogen. That makes alpha-tocopherol a
much better antioxidant because when
alpha-tocopherol donates an electron it
needs to stay stable until it can reach
vitamin C to be recycled. When it donates an
electron it is now a free radical and so
it's in great danger of pairing up that
electron before it gets to vitamin C. So
what it does is it passes the unpaired
electron from one methyl group to the
next like a hot potato and that
circulation of the unpaired electron
from one to the next to the next to the
next is something called resonance
that is a chemistry term. If you look
at gamma tocopherol it only has
two methyl groups, so it will pass back
and forth the unpaired electron like a
hot potato but it can't keep it stable
anywhere near as well as alpha-tocopherol can
because it only has this small space of the ring
that can engage in this resonance
instead of this large space fully around the ring.
So alpha-tocopherol is preferentially
recirculated, probably because it is a
much better antioxidant than the other
forms.
However, you could make a case that gamma
tocopherol may have unique roles that
alpha tocopherol doesn't have. When we
look at superoxide, one of the things
that it can do is react with nitric oxide
to form for peroxynitrite and peroxynitrite
is a very dangerous reactive
nitrogen species because gamma-tocopherol
does not have a methyl group here
it can accept nitrogen where
alpha-tocopherol can't.
and gamma-tocopherol can scavenge peroxynitrite
to form a stable product known
as nitro-gamma-tocopherol or NGT. So it may be
the case that gamma-tocopherol plays a
unique role in scavenging reactive
nitrogen species. To date, we don't really
know that gamma tocopherol is uniquely
important, but we do know that natural
diets would always lead to circulating
gamma-tocopherol in the blood and natural
diets would always contain a mix of
different tocopherols and tocotrienols.
If you consume an alpha-tocopoherol
supplement that instead of providing 10
or 15 or 20 milligrams, like you could
maybe get from food, provides 100, 200
300, or 400 milligrams, then alpha-tocopherol
goes into the liver, is ten times
more likely to be
recirculated into the blood, and if you
have ten times more alpha-tocopherol than
other forms of vitamin E, you're gonna wash
out alpha-TTP. Alpha-TTP is going to be
flooded by nothing but this
alpha-tocopherol that has such a high
affinity for it and you're going to drown
out the other forms of vitamin E like gamma-tocopherol
in the blood. And vitamin E
supplementation with alpha-tocopherol has been shown
to cut gamma tocopherol levels by
large amounts. So what that means is that
it's wise that if you're going to take a
vitamin E supplement, it should contain
some gamma-tocopherol and some of the
other forms of vitamin E. My personal
preference is to use things like
grass-fed butter and palm oil. Palm oil is
rich in the full spectrum of tocopherols
and tocotrienols, so I think it makes
more sense to use moderate doses of the
full spectrum of vitamin E forms than to
use high doses of just alpha-tocopherol
but that doesn't change
the fact that our bodies really seem
hardwired to preferentially recirculate
alpha-tocopherol
and we know from chemistry that alpha-tocopherol
is the most superior
antioxidant out of all forms of vitamin E.
So let's not megadose with alpha-tocopherol
and drown out all the other forms, but
let's also not lose sight of the fact
that alpha-tocopherol is super important
and there's more evidence behind
it's importance than there is for any of the
other forms of vitamin E. So what we
wouldn't want to do is try to develop a
supplement that just has gamma-tocopherol in it,
or that only emphasizes
these other forms of vitamin E
without including alpha-tocopherol, which
we know to be important.
All right, so to sum up, when you're
looking at foods the vitamin E to PUFA
ratio is a better index of how good a
food is as a source of vitamin E than
only looking at the amount of vitamin E
in that food. When you eat vitamin E you need to
eat it with fat to absorb it, and it's better
to get a full spectrum of natural forms
of vitamin E than to megadose with only alpha-tocopherol
because it could drown out the
other forms.
So this was vitamin E, next time is
vitamin C, and we'll continue to take
apart each part of the antioxidant
defense system as we move along.
Signing off this is Chris Masterjohn of
ChrisMasterjohnPhD.Com, and
you've been watching Masterclass With Masterjohn,
and i'll see you in the next
video.
-------------------------------------------
TMS 有關楓葉戰士技能的日記 - Duration: 5:30.
For more infomation >> TMS 有關楓葉戰士技能的日記 - Duration: 5:30. -------------------------------------------
A Casa do Mickey Mouse em Português 🍎GAMEPLAY 🔴Encontre o Personagem💚 Mickey, Pateta,Pluto,Minie - Duration: 13:01.
For more infomation >> A Casa do Mickey Mouse em Português 🍎GAMEPLAY 🔴Encontre o Personagem💚 Mickey, Pateta,Pluto,Minie - Duration: 13:01. -------------------------------------------
Moxxi's Journal - Edgy Chili - Duration: 1:55.
For more infomation >> Moxxi's Journal - Edgy Chili - Duration: 1:55. -------------------------------------------
Soluzioni d'inizio anno per facilitare l'accesso al credito della tua PMI (Parte 2) - Duration: 4:12.
For more infomation >> Soluzioni d'inizio anno per facilitare l'accesso al credito della tua PMI (Parte 2) - Duration: 4:12. -------------------------------------------
Kia Picanto 1.0 LXE AIRCO - Duration: 1:21.
For more infomation >> Kia Picanto 1.0 LXE AIRCO - Duration: 1:21. -------------------------------------------
Rayman 3: Hoodlum Havoc #19/FIN - FINAL BOSS & ENDING ! - Duration: 29:28.
For more infomation >> Rayman 3: Hoodlum Havoc #19/FIN - FINAL BOSS & ENDING ! - Duration: 29:28. -------------------------------------------
YOUTUBERS SECUESTRAN UN HOMBRE. INCREIBLE VÍDEO... - Duration: 1:54.
For more infomation >> YOUTUBERS SECUESTRAN UN HOMBRE. INCREIBLE VÍDEO... - Duration: 1:54. -------------------------------------------
Browse coloring antistress from Aliexpress - Duration: 2:42.Anti-stress coloring is the direction, which very quickly gained its popularity.
A fairly simple but effective method to remove anxiety
and creativity for adults and children.
Today I show the review of the coloring antistress "Alice in Wonderland".
Goods AliExpress
Reviews
Hello!
You at the channel "Goods AliExpress".
On Aliexpress you can find a very large variety of coloring books at affordable prices.
The number of minimal pages that I had found, was 24, with the cost from $1.34.
Coloring book on 80 pages, called "Alice" I bought for $11.39.
Cover and leaves of the notebook are pretty tight,
so crayons and markers are not interrupted on the other side.
The drawings are very interesting and varied.
Contain, as little details that need more attention, and large.
Of course, they are all on the theme of fairy tale "Alice in Wonderland".
Anti-stress coloring pages for adults are a great way of relaxing,
meditation, and entry into the stress space.
This coloring is more complex than normal children,
so it will be interesting for people of any age.
I was left in awe.
The pictures are very beautiful and bright.
It all depends on your imagination.
To buy anti-stress coloring, you can by link in the description.
And don't forget to subscribe and like this review =)
-------------------------------------------
Treasure Island - Interactive Game for Kids series "Magic Lantern" - Duration: 5:43.
Treasure Island - Interactive Game for Kids series "Magic Lantern"
-------------------------------------------
Jovens Titãs em Ação - Sanduiche Lendário e Amamos uma Torta - 1ª Temporada - 1 e 2 Episódio - Duration: 21:00.
For more infomation >> Jovens Titãs em Ação - Sanduiche Lendário e Amamos uma Torta - 1ª Temporada - 1 e 2 Episódio - Duration: 21:00. -------------------------------------------
How to run Jubeat/SDVX hdd with e-amuemu(English CC subtitles) - Duration: 1:10.
Hey guys!Today i'm going to show you how to run HDD with e-amuemu!
First,you can go Jubeat file,prop and you can see ea3-config.xml data.
and then,go edit it.
You can press Ctrl+F to find http://localhost:8080/
change it into htttp://127.0.0.1/core/services/
As you can see.Finally we can run e-amuemu to run HDD!
thanks for watching!(noob english)
-------------------------------------------
Aura Kingdom Cap. 1 E comienzo - Duration: 11:38.
For more infomation >> Aura Kingdom Cap. 1 E comienzo - Duration: 11:38. -------------------------------------------
S.Pellegrino® Water
For more infomation >> S.Pellegrino® Water-------------------------------------------
DIY Mickey Felt Pin For more infomation >> DIY Mickey Felt Pin-------------------------------------------
Volvo V60 20% D3 AUT. R-Design Scandinavian, Nav, Tel - Duration: 1:47.
For more infomation >> Volvo V60 20% D3 AUT. R-Design Scandinavian, Nav, Tel - Duration: 1:47. -------------------------------------------
Should We Grow Human Organs In Pigs? - Duration: 3:19.
Hi - this is Kate from MinuteEarth.
In the United States alone, 22 people die every day waiting for a kidney, liver, heart,
or lung transplant.
There simply aren't enough donated human organs to go around, and we can't just go
around stealing them out of random healthy people.
But pigs' organs have roughly the same structure and proportions as human organs – and we
already kill half a billion of the creatures every year for food – so why can't we
just use their organs?
Here's the thing - our immune systems are really, really good at seeking out and destroying
anything foreign to our bodies, so even human-to-human organ transplants sometimes get rejected.
And pig organs are much foreign-er: they have a super-conspicuous sugar molecule on the
surface of their cells that's basically a "fight me" sign for humans' organ-rejecting
antibodies.
But we've actually been able to engineer pigs whose organs don't carry those sugars, so
assuming we could take care of pig organs' other "fight me" signs in similar ways,
we might one day be able to transplant pig organs into humans.
But there's a far more radical idea for pork-based organ farming: grow customized human organs
in pigs.
Actually, it's not just an idea – it's an ongoing experiment in real life.
First, we engineer a pig embryo that doesn't grow its own kidneys.
Then, we inject it with stem cells from the person needing a transplant.
Then, as the modified pig embryo develops, those human cells grow inside the oinkubator
into healthy kidneys made from the patient's own cells.
At least, that's the plan.
So far, we've only seen this experiment all the way through when the modified pig
embryos were injected with stem cells from other pigs.
We don't know whether it'll actually work with human kidneys, because we've halted
all experiments with the pig-human embryos after just four weeks of development, because...some
of those human stem cells could develop into other human organs elsewhere in the pig's
body - which raises a lot of ethical questions, like what to do with them.
Even if the cells don't migrate and these hybrid pigs end up producing lots of live-saving
organs, what rights do we give to a part-human pig, even if the part is just a kidney?
What if it's two kidneys?
Two kidneys, a liver, and a set of lungs?
In principle, we could use the same technology to grow human hearts, human spinal cords,
and even human brains - all inside of a pig.
And when we do, how will we know if that pig is still a pig?
This episode of MinuteEarth is supported in part by Tab for a Cause.
If you're like me, you open a lot of tabs in your browser.
Tab for a Cause is a browser extension that donates to charity with each new tab you open,
which means lots of money for nonprofits like Conservation International and Human Rights
Watch - without costing you a thing.
The last time we featured Tab for a Cause, MinuteEarthings like you raised more than
$10,000 - click the link in the description to help us do even better this time.
And while you're down there, will you find the notification bell next to the subscribe
button, and click on it?
YouTube has changed the way it notifies subscribers, and this is the best way to make sure you
find out when we post a new video.
You can do the same thing on your phone or tablet.
If you don't see the bell, make sure you're subscribed in the first place.
Thanks, and see you next time!
-------------------------------------------
YOU NEED THIS! 2017 Nissan Sentra NISMO REVIEW - Duration: 4:08.every generation of the nissan sentra
sent the early 1990s proudest 40 variant
most of the potted up small cars have
worn the FDR batch rename that earned a
fair share of credibility after the b13
generation sentra se-r captured
enthusiasts parts and appeared more than
once on TV and best cars list thanks to
hike on your dollar ratio now and it's
pumping up is no performance on nissan's
put the name on the latest offensive
performance very it helps make a
connection among all of the sun's
performance-oriented offering was
probably the juke nismo and Loretta the
370z Nismo and the top dog
600-horsepower gt-r Nismo but the center
and his MO is not a racetrack slaying
high-performance be far from it in fact
given that it has just 188 horsepower
and 177 pounds to put of torque from the
one got six litre turbocharged
four-cylinder that's the lesson was
offered in the last century fer
available from 2072 2012 which had 200
horsepower and 180 pounds to foot of
torque from a to God five liter
four-cylinder engine it's also far short
of the books wagon GI 210 or 220
horsepower the Ford Focus that's key 252
horsepower and the subaru WRX 268
horsepower
of course power isn't everything
particularly considering the center and
is most estimated starting price of less
than twenty-five thousand dollars after
all cars like the 197 horsepower ford
fiesta st prove that outright speed is
far from his sole measure of a card fun
factor to that end is more went to work
on the center's chassis compared with
the identically powered sentra sr
turboed the mismo has a slightly lower
ride height difference springs in
Richmond dancers additional structural
bracing and one inch larger wheels shot
with 215 / 45 r18 ultra high performance
all-season tires summer tires are
available as a dealer and tall adoption
after a quick drive around Los Angeles
in the center is mom we're pretty
Vincent it won't unsee our current
favorites such as the GI but that's not
to say there's nothing to like about the
nismo the little one Coptic liter
engines ft enough once on the boil
there's some turtle like download the
range but the six-speed manual has
relatively short hearing that makes it
easy to keep the engine in the need of
historic curve
there's also a continuously variable
automatic transmission available as a no
cost options we didn't get the chance to
drive a centrist ill-equipped but we can
safely say we pack on that transmission
we do wish mismo had gone a bit further
with the shaft retweet turning could be
sharper and steering feel is nothing to
write home about the nismo suspension is
noticeably different live lesser
centrist but it's tuning seems to
negatively impact ride quality more than
improve handling prowess the likeness of
control the series shifters and clutch
combined to make the center-field
possible leave netted eight-page push
harder and its economy car routes become
all too obvious
-------------------------------------------
Comrade Babunashvili - Duration: 17:24.
Tamuna, Tamuna
Yes?
Get up, it's already half past! Giorgi!
Giorgi! Harry up.
My father was a real communist, I say it with pride.
A real communist.
And from 1989, when the dissolution of the USSR started, I was in the 7th grade.
My father taught, explained, and told us that this was the only true and genuine ideology,
which brought happiness, freedom, and equality for every person,
and it was a huge mistake to ruin this country and this system.
When I grew up and started to think independently, I began to reflect on my childhood
and the period when I was a student, when I was young, and it was very harsh.
You know how hard the '90s were, and I realized that everything my father told me was true.
I had problems regarding tuition - it became expensive.
But before that, I knew that education was free.
There were problems with healthcare. Every aspect of life brought problems,
which I never felt before during the USSR, although I was a kid back then.
Come here, Tamuna.
Fix your hair yourself.
Today, in the morning, Mr. Temur, I posted a greeting of the Stalin Communists on Zviganov's Facebook page.
He would be very happy.
"Happy birthday, Bessarionovich [Son of Bessarion], from the Georgian Communists"
I posted it to Putin's party, Edinaia Rossia's page.
What did you post to Edinaia Rossia?
I posted about Stalin.
he put a joke
What, about Stalin? That it's his birthday.
-We should send a condolence card. -Will they respond?
They killed the ambassador.
The first World War started with the murder of the Ambassador, Birbach.
They didn't kill Birbach, they killed Franz Ferdinand.
I lit up the 'crying candle' for a Russian soldier.
Birbach was a German ambassador in Russia and Essers killed him in 1918, and they wanted to…
No, they killed him but the war neither started nor ended because of him.
When I became a member of the party, I told them that this was my decision,
and you can join me or not, it's not obligatory, I won't be mad.
I told them, if they wanted, they could join me to rally together, and they said they wanted to.
Of course, it was their childish wish, interest, and childish curiosity.
I told her who the pioneers were; how they affected people's lives, freedom, human rights.
When I told them, they could join the pioneers, they agreed.
Now, I can't say that it was their independent choice,
I'm their mother, the parent, and my word, frankly saying, had an influence on them.
They didn't say they were afraid or did something because I told them to,
but I think I had an influence and I can't prove the opposite.
Then I bought his book, The Pioneer Rules.
They read it, saw how their peers lived, how they sacrificed themselves,
they learned the pioneers' oath and joined the pioneers group.
Sosoia, I'm not being sold out like them from the very first day
Shame on the people of Gori, they said they'd change Stalin's street.
When they removed the statue, they didn't say anything, now they are sleeping and not even coming out in the streets.
Shame on the Gori government, because today this Christmas tree stands here instead of the monument of Stalin.
I wanted to say this. Shame on Gori and its people.
This system, a capitalistic system where we live in, lets just a few people live and it suffocates millions of people.
These people will rise, when they'll have enough, when they'll have nothing else to lose.
The revolution of 1917 was the same rising. Before this explosion happened, nothing was there.
And one more thing, this is my personal opinion,
I can't comprehend, how these hot shots would surrender without bloodshed, with just elections.
This blood must be shed, people won't rise without the revolution.
Stand here.
Push further.
Lower, lower, where the rains fall. Not that, this.
The social background, where these children live, helps me to show my children the positive side of socialism.
This children are deprived of nice days, they have never had a childish day.
When I went to the university, somebody would approach me and tell me that I'm a public enemy, because I'm a communist.
I wasn't even a communist by then, but they would say that I'm the enemy of the national movement.
But you know what?
This aggression, and argument didn't affect my self-esteem,
it made me stronger, harder, and gave me more motivation to show them what was genuine and what was a lie.
And it's really true. You might be surprised now, but I'm telling you the truth.
I have tried this before and I'm trying it now too.
Everyone in this building knows that I'm a communist.
I think they respect me because of this, but they don't believe that the system will be back.
-Do you believe it? -Yes, of course!
-------------------------------------------
Education Panel Advances Tax Credits for Private School Tuition - Duration: 2:08:28. For more infomation >> Education Panel Advances Tax Credits for Private School Tuition - Duration: 2:08:28. -------------------------------------------
Browse coloring antistress from Aliexpress - Duration: 2:42.Anti-stress coloring is the direction, which very quickly gained its popularity.
A fairly simple but effective method to remove anxiety
and creativity for adults and children.
Today I show the review of the coloring antistress "Alice in Wonderland".
Goods AliExpress
Reviews
Hello!
You at the channel "Goods AliExpress".
On Aliexpress you can find a very large variety of coloring books at affordable prices.
The number of minimal pages that I had found, was 24, with the cost from $1.34.
Coloring book on 80 pages, called "Alice" I bought for $11.39.
Cover and leaves of the notebook are pretty tight,
so crayons and markers are not interrupted on the other side.
The drawings are very interesting and varied.
Contain, as little details that need more attention, and large.
Of course, they are all on the theme of fairy tale "Alice in Wonderland".
Anti-stress coloring pages for adults are a great way of relaxing,
meditation, and entry into the stress space.
This coloring is more complex than normal children,
so it will be interesting for people of any age.
I was left in awe.
The pictures are very beautiful and bright.
It all depends on your imagination.
To buy anti-stress coloring, you can by link in the description.
And don't forget to subscribe and like this review =)
-------------------------------------------
Dads Who Play Barbie® For more infomation >> Dads Who Play Barbie®-------------------------------------------
The Existence of God For more infomation >> The Existence of God-------------------------------------------
Can't see changes to your website? - PixelTV Ep. 39 - Duration: 1:51.
[Laughing] I actually got that...
Hi, PixelTV fans!
Here's something we sometimes run into.
A client will request a change to their website, and once I tell them it's made, they aren't
able to see it!
Now, of course, everyone's pretty nice about it.
But you can imagine why they might be frustrated!
Luckily, I know a solution that works a lot of the time.
This isn't always the case, but a lot of times when you can't see a change or update to
your website, that's because the old version is saved in your browser history.
Our super fancy technical term for that is to say, "Your website is cached."
So, you just need to refresh your cache to fix the issue.
You could say that you need to get your cache un-cached.
Maybe don't, though.
Okay.
To fix the solution, you need more than just a normal refresh.
You need a hard refresh.
For Mac users, a hard refresh is holding down Command, Shift, and R.
For my PC friends, you'll do a hard refresh by hitting Control and F5.
You can also check to see if your website is cached by opening an incognito window.
If you can see the change in the incognito window, that means
the change or update has happened!
If you can't see it, well, then that's a good time to ask your web developer
to look into it.
If you enjoyed this episode, be sure to subscribe!
Next time, Leann will share how you can crop images in WordPress.
You can subscribe at tandsgo.com/youtube.
[sighs]
-------------------------------------------
Opel Corsa 1.0T S&S 66KW INNOVATION 5DR - Duration: 1:29.
For more infomation >> Opel Corsa 1.0T S&S 66KW INNOVATION 5DR - Duration: 1:29. -------------------------------------------
Dethleffs Globebus T 4 - Duration: 1:24.
For more infomation >> Dethleffs Globebus T 4 - Duration: 1:24. -------------------------------------------
Dethleffs Advantage 6611 T - Duration: 1:26.
For more infomation >> Dethleffs Advantage 6611 T - Duration: 1:26. -------------------------------------------
The Spacies - Hesitate (Anki Remix) - Duration: 3:30.
You don't need to hesitate No, it's not too late
And I wouldn't go without you I might be able to ease your mind
Yes, it's magic Don't believe me? Just watch me watch you
This unraveling thread ends And in your defense
You don't even know me And it makes no sense
But if you seek you will find it Yeah, I'm the king of second chances and one more tries
I'll give you love You wanted nothing
It's chemical Hold onto something
We've got enough So why the wait You don't need to hesitate
I'll give you love You wanted nothing
It's chemical Hold onto something
We've got enough So why the wait You don't need to hesitate
I couldn't believe my eyes Caught me by surprise
Wherever you go I'll follow Say whatever you need to say
Take my breath away Just keep it until tomorrow
This unraveling thread ends And in your defense
You don't even know me And it makes no sense
But if you seek you will find it Yeah, I'm the king of second chances and one more tries
I'll give you love You wanted nothing
It's chemical Hold onto something
We've got enough So why the wait You don't need to hesitate
I'll give you love You wanted nothing
It's chemical Hold onto something
We've got enough So why the wait You don't need to hesitate
To hesitate...
-------------------------------------------
THE MOST COMMON MISTAKES OF A TAX FREE SAVINGS ACCOUNT (TFSA) | Financially Fabulous with Limor - Duration: 5:46.
welcome to another financially fabulous
episode I'm Limor
and while i'm not a financial planner
i'll show you what I've learned in
today's episode I'm going to be talking
about the top four things you likely
don't know about your TFSA come on this
will be fabulous
TFSA is tax-free savings account and it
was an account the Canadian government
introduced back in 2009 since it's been
around
it's a great opportunity for us to
invest money for the short term and not
have to pay tax on the gains with this
account for some reason I have no idea
why it's got so many people confused
and make lots of mistakes with this
various account i'm going to go through
the top four things that you probably
don't realize about this account
item number one is that with a tax-free
savings account
you don't have to pay tax on your
capital gains so if you have some money
in your tax-free savings account and you've
put it into an investment and that
investment grows over time the
difference of the growth in that
particular investment
you don't have to pay taxes on you do
however have to pay tax when you earn
the money originally before you put it
into your tax-free savings account but
on the money that you've invested inside
the account when it grows you don't have
to pay tax and by not paying tax you
actually allow your investment to grow a
lot faster
the second thing that you may not
realize is that every year there is a
limit to how much money you put into
that account
it's called a contribution limit or your
contribution room every year since 2009 there
has been a fixed amount of money that
you can put into that account for 2016
and 2017 the amount that you can put in
is $5500
the reason this is important is because
if you're Canadian and you're over the
age of 18 and you haven't been putting
money into your TFSA every single year
the room from previous years is actually
available there for you
I also think it makes for a really good
target to try to put that money aside if
you could save $5500 this year in
2017 I think that'd be a great start so
start putting money in there on a
regular basis or if you get a bonus or a
hefty birthday gift cheque you can put
the money in there as well
the third thing that you may not realize
about the tax free savings account
is that if you take money out in a
particular year and you go to put it
right back in if you're not using the
contribution limit of a previous year
you actually have to pay a penalty so
unlike the regular savings account where
maybe you'll take the money out and
you'll go on a vacation or buy something
awesome that you've been wanting and
then when you save the money you put it
back in with the TFSA account if you take
the money out this year that room is not
available to you until the following
year the fourth thing that you may not
realize as this is probably the biggest
mistake that I see people doing all the
time if they put money into a TFSA
thinking oh yes I'm doing the right
thing I got my money in my TFSA and then
I ask them what is invested in and
they're like ummm.... invested it's in my tfsa if
you just take your cash put it in your
TFSA and don't actually invest it's
not going to grow and that defeats the
whole purpose of a TFSA when your
money grows that's when you don't pay
tax you just leave your money in cash
well you might as well just leave it in
your chequing account so if you've got
10,000 dollars and you invest in a
five percent interest for one year
you're going to have 10,500 dollars
now if you left that
money in cash at the end of the one-year
you only have 10,000 dollars with
the tax-free savings account that extra
500 dollars that you make you
don't have to be taxing and that is the
great benefit of the tax-free savings
account that brings me to my Tweetable
today take advantage of tax benefits
with a TFSA you want to understand how
the account actually works so that you can
make it work to your full advantage
here's my challenge to you if you don't
already have a TFSA I want you to go and
set one up you can set one up with
whatever bank you're already using right
now and for 2017 as i mentioned the
limit is five thousand five hundred
dollars and my challenge to you is to see if
you can set that money aside
don't forget to access the free
downloadable below here at limor.money
in the downloadable I've included
the history of the tfsa and
how much contribution room there has
been available to us Canadians since 2009
that way if you've not taken advantage
of all the room in the past you can take
advantage of it and put some money into
that account did you like this video
did you learn something subscribe to my
channel because it's free and share
with your friends and if you want even
more tips and tricks to make your
finances but exciting
come on over to www.Limor.Money and
sign up for email updates
remember i'm not here to change who you
are or how you live your life
I just have strategies to make you even more
financially fabulous thank you so much
for watching I'll catch you next time
till then... stay fabulous
-------------------------------------------
Neil Lane Bridal "Like They Use To" :15 Commercial from Kay Jewelers - Duration: 0:16.
Neil Lane designs jewelry for Hollywood's biggest stars
and at Kay Jewelers he designs them for you, too.
"You know the saying, 'They don't make them like they use to?'"
"I still do."
Kay, the number one jewelry store for…
"Yes!"
-------------------------------------------
Save the Bay - Duration: 4:08.
WE'LL TALK, TOO, MORE ABOUT ALL
THE OTHER GOODY DIDS THAT HE'S
BROUGHT ALONG WHEN WE COME BACK.
Will: IT MAY BE CHILLY, BUT
TIME NOUL IS FOR A LITTLE
CRUISE IN THE OCEAN STATE.
EACH WINTER, HARBOR SEALS
MIGRATE SOUTH FROM MAINE AND
CANADA AND CAN BE FOUND HERE IN
SOUTHERN NEW ENGLAND AND YOU
CAN SEE THEM AS YOU BEAT YOUR
WINTER CABIN FEVE WEATHER A
TOUR RIGHT ALONG THE
NARRAGANSETT BAY.
HERE TO TELL US ALL ABOUT IT,
BOAT CAPTAIN AARON FUHRMAN AND
DAVE BLUNT FROM SAVE THE BAY.
GOOD MORNING, GUYS.
GOOD MORNING.
Will: GOOD TO HAVE YOU HERE
TODAY.
WE TALKED TO SAVE THE BAY
BEFORE AND I KNOW THESE TOURS
EXIST.
IT'S SOMETHING I ALWAYS WANDED
TO DO AND IT REALLY IS A GREAT
DAY, A GREAT ADVENTURE FOR A
FAMILY TO CHECK THIS OUT.
IT SURE IS.
SO WE'VE BEEN DOING THESE TRIPS
NOW, THIS IS OUR 16TH YEAR.
Will: WOW!
SO, IT'S A GREAT THING AND
IT'S REALLY BECOME A
QUINTESSENTIAL RHODE ISLAND
EXPERIENCE.
Will: SO TELL US ABOUT THE
TOUR ITSELF.
OBVIOUSLY WHERE IT LEAVES FROM
AND REALLY THE EXPERIENCE THAT
YOU GET ALONG THE ROUTE AS
YOU'RE CHECKING OUT THESE SEALS
AND MAYBE SOME OF THE OTHER
THINGS THAT YOU MAY SEE.
WE LEAVE OUT OF BOWEN'S
WHARF RIGHT NOW IN NEWPORT AND
WE DO A SCENIC CRUISE AROUND
THE HARBOR.
HEAD OUT RIGHT OFF OF ROSE
ISLAND.
SO, WE GET TO SEE ROSE ISLAND
AND PULL INTO SIGHTING ROCK AND
WE'VE BEEN SEEING THIS TIME OF
YEAR, AVERAGING BETWEEN ABOUT
20 AND 40 SEALS SWIMMING AROUND
AND LAYING OUT ON THE ROCKS.
Will: WOW.
OBVIOUSLY WE CALL RHODE ISLAND
-- RHODE ISLAND IS THE OCEAN
STATE.
BUT A LOT OF PEOPLE FORGET SOME
OF THE MARINE LIFE THAT'S RIGHT
IN OUR BACKYARD.
RIGHT OUT THE DOOR THAT YOU CAN
SEE AND GET CLOSE TO ALL THE
TIME.
YEAH.
A LOT OF PEOPLE ARE SURPRISE
HAD THE WE HAVE SEALS HERE IN
THE OCEAN STATE.
REALLY THEY WERE ABSENT FOR
MANY YEARS.
IT WASN'T UNTIL THE PASSAGE OF
THE MARINE MAMMAL ACT IN 1972
THAT THEIR NUMBERS STARTED TO
INCREASE.
SO, WHEN MOST OF US WERE
GROWING UP, THERE WEREN'T ANY
SEALS.
Will: WE SAID THEY MIGRATE
FROM CANADA AND FURTHER UP
NORTH.
WHAT BRIDGESING THEM TO RHODE
ISLAND AND MAYBE NOT THE OTHER
PLACES ALONG THE EAST COAST?
MAYBE THEY SHOULD HEAD TO
FLORIDA WHERE IT'S WARMER.
[LAUGHTER]
YOU WOULDN'T FIND THE FOOD
THAT YOU ARE LOOKING FOR.
SO, THEY'RE FOLLOWING THEIR
FOOD SOURCE, WHICH IS HERRING,
MACKEREL.
SO WE GET DECENT SIZE SCHOOLS
OF THEM THAT COME DOWN.
THEY ARE FOLLOWING THE LITTLE
BIT WARMER WATER AND THE SEALS
FOLLOW THEM DOWN.
Will: WHAT IS THE REACTION
OF FOLKS?
A LOT OF PEOPLE DON'T HAVE A
CHANCE TO HEAD DOWN
NARRAGANSETT BAY AND SEE THINGS
LIKE THIS.
OBVIOUSLY THERE ARE KIDS DOWN
THERE.
WE HAVE VIDEO OF THEM WITH
BINOCULARS CHECKING THEM OUT.
WHAT IS THE REACTION?
FIRST OF ALL, WHEN WE HEAD
OUT THROUGH THE HARBOR, WE HAVE
ALL THE BUOYS AND EVERYTHING
OUT THERE AND KIDS IMMEDIATELY
THINK THAT THOSE ARE SEALS.
[LAUGHTER]
THEY JUMP THE GUN A LITTLE BIT.
BUT ONCE THEY GET OUT THERE,
EVERYONE IS GLUED TO THE SIDE
OF THE BOAT.
THEY HAVE THEIR BINOCULARS AND
IT IS SOMETHING THAT THEY
NORMALLY WOULDN'T SEE.
Will: SO, WHAT DO WE GET TO
SEE WHEN WE'RE ON THIS TOUR?
WHAT ARE SOME OF THE OTHER
THINGS -- OBVIOUSLY CHECKING
OUT THE SEALS -- BUT I'M SURE
YOU'VE SEEN OTHER THINGS ALONG
THE ROUTE WHILE YOU'RE OUT
THERE AS WELL.
WE'VE SEEN A FEW THINGS.
OCCASIONALLY WE'LL SEE SOME
OTHER KINDS OF SEALS,
ESPECIALLY GRAY SEALS, THAT
WILL OCCASIONALLY SHOW UP HERE.
WE'VE SEEN PORPOISE ON OCCASION.
WE DIDN'T GET A CHANCE TO SEE
THE HUMPBACK WHALE LAST YEAR.
WE LOOKED FOR IT.
BUT DIDN'T SEE THAT ONE.
Will: AND IS IT STILL AS
EXCITING FOR YOU EVERY TIME YOU
JUMP ON THIS BOAT AND HEAD OUT?
EXCITING FOR WHAT YOU ARE GOING
TO SEE?
IT'S MORE EXCITING JUST TO
SEE THE PEOPLES' REACTIONS.
ESPECIALLY SOMEONE WHO HASN'T
BEEN ON THE BOAT BEFORE AND
THEY'RE GETTING OUT THERE AND
JUST SEEING SOMETHING --
Will: YEAH.
IT REALLY IS WHEN YOU ARE OUT
ON A BOAT LIKE THAT AND GOING
UNDER THE NEWPORT BRIDGE OR
JAMESTOWN BRIDGE, RHODE ISLAND
HAS A LOT TO OFFER AND REALLY
IS BEAUTIFUL NO MATTER WHAT
TIME OF YEAR.
GUYS, THANK YOU FOR JOINING US.
GREAT STUFF.
I'D LOVE TO GO ON ONE OF THOSE
TOURS.
YOU CAN CHECK OUT SAVE THE BAY
SEAL WATCH AND NATURE CRUISES
RIGHT NOW.
YOU CAN HEAD TO rhodeshow.com
-------------------------------------------
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VMO Squats - Ask Doctor Jo - Duration: 0:28.
For a VMO squat, you're going to work the inner quad
muscle. Turn your feet out at about a
45-degree angle, but you're still going
to stick your bottom back and bring your
chest forward so your knees don't go in
front of your toes.
You're going to squat down and out.
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Tous En Scène, ma critique SANS SPOILERS ! - Duration: 7:46.
For more infomation >> Tous En Scène, ma critique SANS SPOILERS ! - Duration: 7:46. -------------------------------------------
Moxxi's Journal - Edgy Chili - Duration: 1:55. For more infomation >> Moxxi's Journal - Edgy Chili - Duration: 1:55. -------------------------------------------
Happy Birthday, Mr. Juggernaut - Duration: 7:16.
We're about two weeks out from the release of 12.1,
Dash got a lot of grassroots coverage in the media this week,
and also it turned three years old -- happy 3rd birthday Dash network!
Hi, I'm Amanda B. Johnson and you're watching DASH: Detailed.
Let's get started with Dash in the News, shall we?
The Merkle mentioned Dash in an article entitled "The Five Hottest Cryptocurriencies Right Now."
Youtuber Tommy Economics published a video describing how his ideal cryptocurrency
would look a lot like Dash.
The Future Tech Podcast interviewed Node40's Perry Wooden about masternode maintenance.
Dash's director of network operations Jeff Smith AKA Coingun,
stepped into the toilet, literally, to give an interview to Bitcoin Uncensored.
Omar Bham, the man who likes to talk crypto in his car,
mentioned Dash in a recent episode of Let's Talk Crypto.
BATT analyzed Dash price charts and movements
quite thoroughly in this episode of Bitcoin & Altcoin Trading Talk.
And Youtuber James Bond made this interesting and pony-filled Dash 3D graphic
for his video where he gives Dash analysis and predictions.
Did you know that there's a My Little Pony called Rainbow Dash?
Now you do.
Let's move to price movement.
Dash's current prices in the neighborhood of 14 US dollars and seventeen cents.
This makes for a market capitalization of roughly 100 million dollars,
with a 24-hour trade volume of 2.6 million dollars,
and just over 7 million coins in existence.
In our 7-day price chart
you'll see that today's market cap is almost identical to what it was seven days ago.
In the interim there was this sort of price arc as you see here,
during which time Dash temporarily displaced Ethereum Classic
for the number-6 spot in market cap rankings.
Speaking of price fluctuations –
community member troydash recently brought to this most excellent tool to my attention,
which can be used by masternodes to see in a glance
the current monthly payout
as well as percentage of the network that they owned per masternode.
Now to Business News.
I almost dare not believe that it's so,
but it appears that there is a comprehensive and detailed website
listing all merchants that accept Dash worldwide.
WeLoveDash.com currently lists 245 plus merchants,
making them the single most comprehensive collection of Dash merchants on the internet.
If your Dash-accepting business is not listed on this website
the admins can be reached via their contact information
or via the Dash Nation Slack, just reach out to user "aristokrat".
There's a new merchant accepting Dash by the name of La Nay Ferme,
which is a biodynamic farm in Provo, Utah selling vegetables and herbs.
And for the third month in a row
Purse.io reports that Dash is the top altcoin used to buy things from Amazon.
Let's check out Network Statistics.
Today's masternode count is 4,277.
This is down 105 masternodes from last week's 4,382.
Or aswas pointed out by some in the Dash Nation Slack --
this means that masternode owners are now getting paid between one and two percent more frequently.
With about 540 non-masternode full nodes open,
we're left with a total of 4,820 full nodes on the network.
And in mining,
today's hashrate is 2.31 Tara hashes per second,
which is down slightly from a new all-time high that was reached a few days ago of 2.36.
And speaking of mining, some have also been asking in the Slack
about purchasing their own mining units.
Thanks to the assistance given them by both Oaxaca and Macrochip
you see that there's a nifty profit calculator on Coinwarz
that you can use with your individual electricity set-up
to see if mining would or would not be profitable for you.
If indeed it is, Dash ASICs sold from Pinidea, Baikal, and iBeLink.
And the next Dash superblock – that is treasury payday –
is in eight days so if you have a masternode and you intend to vote,
you want to get those in shortly.
Now to Social Happenings.
Dash now has a presence on Pinterest.
Yes, you heard me right, Pinterest.
While luddites such as myself thought the site was primarily for
recipes, pictures of wedding dresses, and arts and crafts tutorials,
cryptocurrency is now representing.
Dash also has a
Telegram news bot if you use Telegram
and would like to subscribe to that news
bot. These handsome gents met up in Cancun,
Mexico at be weekly Dash sponsored
Bitcuners meetup. The meetup is
organized by Dash community member JZA.
And the first Dash meetup has taken
place in Russia hosted by community
member
Milliarderko in the city Krasnodar.
Milliarderko reports that 15 people
showed up and of them six knew nothing
about cryptocurrency. The Crypto Show,
continuing its sponsorship from Dash, has
released this video of them helping
prepare meals for the homeless with the
project UnSung. This video, also by
Youtuber Crypto shows Jeff Smith AKA
Coingun giving an exemplary explanation
of Dash to a newcomer. The explanation
took place at The North American Bitcoin
Conference where the same Youtuber also
recorded and published Ryan Taylor,
director of finance at Dash, giving his
presentation. This presentation was so
popular that a bounty was created for it
to be remade with improved audio, and
that has been done. And we have ourselves
a comment of the week!
Yes, it's from a Chris Muller, and he said
on Youtube, "I think Dash has already
become an unstoppable feedback loop.
I'm beginning to sense the birth of a
cryptocurrency juggernaut, A
cryptocurrency juggernaut – take that to
the Dash bank that you are. And finally,
Current Opportunities. The Dash Force is
holding a meetup contest.
This means that if you're willing to
agree to a few parameters such as
purchasing refreshments and then giving
your attendees Dash with which to buy
those refreshments from you, you can get
paid around
hundred and ten dollars in Dash for
holding a meetup. It doesn't matter where
you live,
doesn't matter who you are all, are
qualified to apply. And that's it for
DASH: Detail this week.
Special thanks and props to Alex-ru
who's beautiful Dash graphics we make
use of frequently. You can find his
gallery of free-to-use images yourself
in the links in the description below.
That's it everyone, see you next
Wednesday.
[Music]
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Ed Sheeran - Shape Of You - Duration: 4:43.
For more infomation >> Ed Sheeran - Shape Of You - Duration: 4:43. -------------------------------------------
Elderly woman lifted out of home in bathtub during tornado - Duration: 2:55.
For more infomation >> Elderly woman lifted out of home in bathtub during tornado - Duration: 2:55. -------------------------------------------
Big Wild - Invincible (feat iDA HAWK) With Lyrics (English) - Turn On Caption (CC) - Duration: 3:50.
For more infomation >> Big Wild - Invincible (feat iDA HAWK) With Lyrics (English) - Turn On Caption (CC) - Duration: 3:50. -------------------------------------------
Secret Service agent says she 'wouldn't take a bullet for Donald Trump' - Duration: 3:37.
Outrage at woman Secret Service agent and Clinton supporter who said she would NOT risk her life to protect President Trump
A senior U.S. Secret Service agent said she wouldn't want to take a bullet for President Trump.
Kerry O'Grady, the special agent in charge of the Secret Service's Denver district, was a vocal opponent of the Donald during his campaign.
She has made several posts on social media in the past year criticizing Trump, saying he would be a 'disaster' for the country - particularly for women and minorities.
And in October, she posted that she would rather go to jail than 'take a bullet' for Trump - although she avoided referring to him by name.
PHOTO: Kerry O'Grady ,the special agent in charge of the Secret Service's Denver district, was a vocal opponent of the Donald during his campaign
'As a public servant for nearly 23 years, I struggle not to violate the Hatch Act,' she wrote, referring to the act that bars executive branch staff from engaging in certain political activities.
'So I keep quiet and skirt the median. To do otherwise can be a criminal offense for those in my position. Despite the fact that I am expected to take a bullet for both sides.'
She continued: 'But this world has changed and I have changed. And I would take jail time over a bullet or an endorsement for what I believe to be disaster to this country and the strong and amazing women and minorities who reside here. Hatch Act be damned. I am with Her.'
Secret Service employees are covered by the act which bars people from posting partisan messages on social media, or sharing and disturbing partisan material, according to the Washington Examiner.
In operational security training, agents are warned against the use of social media because it can expose their personal information and their movements, sources say
That post triggered at least one complaint to the Secret Service, those sources added.
The Secret Service confirmed that they are aware of O'Grady's tweets and are 'looking into the matter.'
PHOTO: 'As a public servant for nearly 23 years, I struggle not to violate the Hatch Act,' she wrote, referring to the act that bars executive branch staff from engaging in certain political activities
O'Grady told the Examiner she took down the post just a couple of days after it was posted.
She explained that she wrote the post shortly after learning that Trump was being accused of sexually abusing a number of women. It was just days after the notorious video of Trump telling Access Hollywood' host Billy Bush he could grab women 'by the p***y.'
As a survivor of alleged sexual abuse, O'Grady said she had written the message while overcome with emotion by the news.
But she took down the post after realizing 'it was not the sentiment that I needed to share because I care very deeply about the mission.'
'My government is the most important thing to me,' she said. 'I serve at the pleasure of the president, but I still have the First Amendment right to say things.' However, that was not the only anti-Trump post O'Grady made.
Over the past few months, she has made multiple political comments showing her support for Democrat Hillary Clinton and criticizing Trump.
O'Grady previously shared a Huffington Post story with the headline: 'Scott Baio Defends Trump's Sexism with More Sexism', with her comment; 'One word: douche. How do you like them apples?!'
A month after her 'bullet' post, she shared a Vox post, headlined 'Donald Trump nominates Jeff Sessions to serve as attorney general' on which Vox commented 'Just a few years ago, this would have been unimaginable.'
O'Grady wrote: 'We are moving our civil rights into a period of bigotry, misogyny and racism that this country has not tolerated for decades. Dark ages. I am horrified and dismayed beyond words.' Even after Trump's election, the agent continued to post.
During the Women's March, she posted the logo for the movement as her Facebook cover. She later posted: 'All of these women represent me! Proud to say it! #nasty,' referring to the phrase Clinton supporters referred to themselves by after Trump labelled Hillary a 'nasty woman.'
PHOTO: O'Grady, who removed the post a couple of days later, said she wrote it after being overcome with emotion following Trump's 'grab them by the p***y' video
On Inauguration Day, she updated her profile picture to a picture of Princess Leia with the words, 'A woman's place is in the resistance' - a reference to the rebel alliance in Star Wars, or those opposing Trump's presidency.
All political posts have since been removed. O'Grady said this week that she is devoted to her mission to serve her country and that nothing would stop her from doing her job.
'I hope you understand that's an emphatic no,' she said when asked if he political stance would affect her job, 'and I need to make sure that's resoundingly clear and just reinforces that this job needs to done well.'
-------------------------------------------
Kazoo Kid Speedpaint - Duration: 3:37.
For more infomation >> Kazoo Kid Speedpaint - Duration: 3:37. -------------------------------------------
Reversible Car Seat Poncho How to | Whitney Sews - Duration: 7:10.
Car Seat Poncho
Hi everyone! I'm Whitney and I post sewing and crafting tutorials here on my youTube
channel. Today I'll be showing how to make the ever popular car seat poncho! This is
very handy because it can be left on while a child is in a car seat instead of needing
to take it off like you would with a coat. This version is fully lined so it is reversible,
does not require hemming any curved edges, it is as cute as can be, and really isn't
that hard to make! But first, before we get into that tutorial, make sure to hit that
red subscribe button down below so you don't miss out on any of my future tutorials. And
hit that bell button as well so you get a notification as soon as a video is posted.
Now onto the materials.
You will need about a yard each of two different materials. I will have the measurements listed
on my website that I used to create my daughter's car seat poncho that I would consider to be
a 2T/3T size. If your kid is larger you will want to get a little more, like 1 ¼ yard
of each.
Once you have your materials you need to make these two simple pattern pieces. Like I said,
I will have all the details and info about creating them over on my website and that
link is in the information icon in the upper corner of the screen.
Now to get into the actual project. Lay your first material out the way it comes off the
bolt with a fold on one side and the selvages lined up together at the other. If you place
your pattern on like that you will have a lot of waste. So you want to refold the fabric
so the selvages are no longer lined up and one end is extending farther, but you still
have enough room for your pattern to fit on. Then fold your fabric in half again. I made
sure the short side is on the outside. Ok, it should look like this with two folded edges
on one corner. A big fold along the other then along the bottom your selvage edges and
the longer excess bit. Place your pattern so the small cut out curve is over the big
folded corner and the straight sides are lined up with the edges with folds. Carefully cut
only along the small curve and big curve.
When you unfold it you will have a piece resembling a donut. I like to use the first one to cut
out the second to make sure they are exactly the same. So lay it flat on your second piece
and cut along the inner and outer circles. I know the inner circle looks small right
now, but trust me, it will work out.
Take a long straight edge and cut straight up from the bottom to the center circle. Then
go in and carefully curve the edges of the cut.
Use the leftover fabric to cut out two hood pieces from each fabric. This is why it was
so important to be as conservative as possible with the material earlier. Sew along the curved
edge of each set using a ½ inch seam allowance. Now we are going to be working with the straight
front edges. So open each set up and put the right sides together lining up that seam from
before. Make sure the seam allowances are going in opposite directions to reduce bulk
and pin or clip the two layers together. Then sew along the entire U shape. Flip it right
sides out and top stitch along the seam you just sewed then continue sewing along the
bottom edge just to make it easier to work with in the next step. Doesn't that hood look
nice?!?
Ok, grab one of the body pieces and open up the front slit a little. You aren't stretching
the fabric, just shifting it so the small circle is more of an oval. Line the hood up
with the opening with the same fabrics touching. Clip them together in just a few spots near
the middle. The easiest way to attach the hood is to start in the middle and sew to
one edge adjusting the layers as you go. Then start back at the middle and sew to the other
edge.
Now it's time to sew everything together. Lay the two pieces right side together with
the hood in between. You may notice the seam across my grey material...if you want to know
more about why that is there check out my sew your stash video linked in the information
button in the upper corner of the screen.
When they are lined up clip in a few places, but don't worry too much about getting it
all lined up because you will need to adjust things as you go. Then sew around the inner
curve, down the straight bit, all the way around the outside and back up into the other
straight area. You need to leave about 8 inches in the straight side open to turn everything
through. It should look like this and as you can see there is the hole for turning.
Reach in through the hole until you can grab the other end of the poncho and pull it all
the way through. Poke out the corners and make sure everything looks good. Then turn
in the edges of the opening and sew it closed and keep topstitching all the way around the
entire thing.
The last thing to do is add your closure. You can go with velcro or a couple of buttons
and button holes, but I decided to use plastic snaps. I used this snap setter here to put
them in and it's super easy there will be a link below if you want to check it out.
And that is it! Like I said, this car seat poncho is cute, practical, and not hard to
make. When it's time to put your kiddo in their carseat you flip the back part up over
the top of the seat and buckle the straps under the poncho. They stay warm in and out
of the car during the winter.
Make sure to like, pin and share if you enjoyed this tutorial and to help grow the Whitney
Sews family to 100,000 subscribers. If you want to see another easy project that uses
a similar pattern you can check out my circle skirts 3 easy ways video that will be linked
right over here. There will also be a playlist full of beginner friendly projects below that.
Subscribe if you haven't already and come back next Wednesday for a new video. Happy
Sewing!
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